| EC |
3.2.1.113 |
| Accepted name: |
mannosyl-oligosaccharide 1,2-α-mannosidase |
| Reaction: |
Hydrolysis of the terminal (1→2)-linked α-D-mannose residues in the oligo-mannose oligosaccharide Man9(GlcNAc)2 |
| Other name(s): |
mannosidase 1A; mannosidase 1B; 1,2-α-mannosidase; exo-α-1,2-mannanase; mannose-9 processing α-mannosidase; glycoprotein processing mannosidase I; mannosidase I; Man9-mannosidase; ManI; 1,2-α-mannosyl-oligosaccharide α-D-mannohydrolase |
| Systematic name: |
2-α-mannosyl-oligosaccharide α-D-mannohydrolase |
| Comments: |
Involved in the synthesis of glycoproteins. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, METACYC, PDB, CAS registry number: 9068-25-1 |
| References: |
| 1. |
Tabas, I. and Kornfeld, S. Purification and characterization of a rat liver Golgi α-mannosidase capable of processing asparagine-linked oligosaccharides. J. Biol. Chem. 254 (1979) 11655–11663. [PMID: 500665] |
| 2. |
Tulsiani, D.R.P., Hubbard, S.C., Robbins, P.W. and Touster, O. α-D-Mannosidases of rat liver Golgi membranes. Mannosidase II is the GlcNAcMAN5-cleaving enzyme in glycoprotein biosynthesis and mannosidases IA and IB are the enzymes converting Man9 precursors to Man5 intermediates. J. Biol. Chem. 257 (1982) 3660–3668. [PMID: 7061502] |
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| [EC 3.2.1.113 created 1986] |
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