The Enzyme Database

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Accepted name: protein-glucosylgalactosylhydroxylysine glucosidase
Reaction: protein α-D-glucosyl-(1→2)-β-D-galactosyl-L-hydroxylysine + H2O = D-glucose + protein β-D-galactosyl-L-hydroxylysine
Other name(s): 2-O-α-D-glucopyranosyl-5-O-α-D-galactopyranosylhydroxy-L-lysine glucohydrolase; protein-α-D-glucosyl-1,2-β-D-galactosyl-L-hydroxylysine glucohydrolase
Systematic name: protein-α-D-glucosyl-(1→2)-β-D-galactosyl-L-hydroxylysine glucohydrolase
Comments: Requires free, positively charged ε-amino group of hydroxylysine.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 72829-45-9
1.  Hamazaki, H. and Hotta, K. Purification and characterization of an α-glucosidase specific for hydroxylysine-linked disaccharide of collagen. J. Biol. Chem. 254 (1979) 9682–9687. [PMID: 385589]
2.  Hamazaki, H. and Hotta, K. Enzymatic hydrolysis of disaccharide unit of collagen. Isolation of 2-O-α-D-glucopyranosyl-O-β-D-galactopyranosyl-hydroxylysine glucohydrolase from rat spleens. Eur. J. Biochem. 111 (1980) 587–591. [PMID: 7460918]
3.  Sternberg, M. and Shapiro, R.G. Studies on the catabolism of the hydroxylysine-linked disaccharide units of basement membranes and collagens. Isolation and characterization of a rat kidney α-glucosidase of high specificity. J. Biol. Chem. 254 (1979) 10329–10336. [PMID: 385599]
[EC created 1984]

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