EC |
3.1.7.10 |
Accepted name: |
(13E)-labda-7,13-dien-15-ol synthase |
Reaction: |
geranylgeranyl diphosphate + H2O = (13E)-labda-7,13-dien-15-ol + diphosphate |
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For diagram of abietadiene, abietate, isopimaradiene, labdadienol and sclareol biosynthesis, click here and for diagram of sclareol and (13e)-labda-7,13-dien-15-ol biosynthesis, click here |
Other name(s): |
labda-7,13E-dien-15-ol synthase |
Systematic name: |
geranylgeranyl-diphosphate diphosphohydrolase [(13E)-labda-7,13-dien-15-ol-forming] |
Comments: |
The enzyme from the lycophyte Selaginella moellendorffii is bifunctional, initially forming (13E)-labda-7,13-dien-15-yl diphosphate, which is hydrolysed to the alcohol. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Mafu, S., Hillwig, M.L. and Peters, R.J. A novel labda-7,13E-dien-15-ol-producing bifunctional diterpene synthase from Selaginella moellendorffii. ChemBioChem 12 (2011) 1984–1987. [DOI] [PMID: 21751328] |
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[EC 3.1.7.10 created 2012] |
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