The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

EC 3.1.3.99     
Accepted name: IMP-specific 5′-nucleotidase
Reaction: IMP + H2O = inosine + phosphate
Other name(s): ISN1 (gene name)
Systematic name: inosine 5′-phosphate phosphohydrolase
Comments: The enzyme, isolated from the yeast Saccharomyces cerevisiae, is highly specific for inosine 5′-phosphate, and has no detectable activity with other purine and pyrimidine nucleotides. Requires divalent metals, such as Mg2+, Co2+ or Mn2+.
Links to other databases: BRENDA, EXPASY, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9027-73-0
References:
1.  Itoh, R. Purification and some properties of an IMP-specific 5′-nucleotidase from yeast. Biochem. J. 298 (1994) 593–598. [PMID: 8141771]
2.  Itoh, R., Saint-Marc, C., Chaignepain, S., Katahira, R., Schmitter, J.M. and Daignan-Fornier, B. The yeast ISN1 (YOR155c) gene encodes a new type of IMP-specific 5′-nucleotidase. BMC Biochem. 4:4 (2003). [PMID: 12735798]
[EC 3.1.3.99 created 2016]
 
 


Data © 2001–2017 IUBMB
Web site © 2005–2017 Andrew McDonald