The Enzyme Database

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EC 3.1.3.97     
Accepted name: 3′,5′-nucleoside bisphosphate phosphatase
Reaction: nucleoside 3′,5′-bisphosphate + H2O = nucleoside 5′-phosphate + phosphate
Systematic name: nucleoside-3′,5′-bisphosphate 3′-phosphohydrolase
Comments: The enzyme, characterized from the bacterium Chromobacterium violaceum, has similar catalytic efficiencies with all the bases. The enzyme has similar activity with ribonucleoside and 2′-deoxyribonucleoside 3′,5′-bisphosphates, but shows no activity with nucleoside 2′,5′-bisphosphates (cf. EC 3.1.3.7, 3′(2′),5′-bisphosphate nucleotidase).
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Cummings, J.A., Vetting, M., Ghodge, S.V., Xu, C., Hillerich, B., Seidel, R.D., Almo, S.C. and Raushel, F.M. Prospecting for unannotated enzymes: discovery of a 3′,5′-nucleotide bisphosphate phosphatase within the amidohydrolase superfamily. Biochemistry 53 (2014) 591–600. [PMID: 24401123]
[EC 3.1.3.97 created 2015]
 
 


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