The Enzyme Database

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EC 3.1.3.84     
Accepted name: ADP-ribose 1′′-phosphate phosphatase
Reaction: ADP-D-ribose 1′′-phosphate + H2O = ADP-D-ribose + phosphate
Other name(s): POA1; Appr1p phosphatase; Poa1p; ADP-ribose 1′′-phosphate phosphohydrolase
Systematic name: ADP-D-ribose 1′′-phosphate phosphohydrolase
Comments: The enzyme is highly specific for ADP-D-ribose 1′′-phosphate. Involved together with EC 3.1.4.37, 2′,3′-cyclic-nucleotide 3′-phosphodiesterase, in the breakdown of adenosine diphosphate ribose 1′′,2′′-cyclic phosphate (Appr>p), a by-product of tRNA splicing.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Shull, N.P., Spinelli, S.L. and Phizicky, E.M. A highly specific phosphatase that acts on ADP-ribose 1′′-phosphate, a metabolite of tRNA splicing in Saccharomyces cerevisiae. Nucleic Acids Res. 33 (2005) 650–660. [PMID: 15684411]
[EC 3.1.3.84 created 2011]
 
 


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