The Enzyme Database

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EC 3.1.3.39     
Accepted name: streptomycin-6-phosphatase
Reaction: streptomycin 6-phosphate + H2O = streptomycin + phosphate
Other name(s): streptomycin 6-phosphate phosphatase; streptomycin 6-phosphate phosphohydrolase; streptomycin-6-P phosphohydrolase
Systematic name: streptomycin-6-phosphate phosphohydrolase
Comments: Also acts on dihydrostreptomycin 3′α,6-bisphosphate and streptidine 6-phosphate.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 9055-33-8
References:
1.  Walker, J.B. and Skorvaga, M. Streptomycin biosynthesis and metabolism. Phosphate transfer from dihydrostreptomycin 6-phosphate to inosamines, streptamine, and 2-deoxystreptamine. J. Biol. Chem. 248 (1973) 2441–2446. [PMID: 4121457]
2.  Walker, M.S. and Walker, J.B. Streptomycin biosynthesis. Separation and substrate specificities of phosphatases acting on guanidinodeoxy-scyllo-inositol phosphate and streptomycin-(streptidino)phosphate. J. Biol. Chem. 246 (1971) 7034–7040. [PMID: 4331203]
[EC 3.1.3.39 created 1976]
 
 


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