| EC |
3.1.3.24 |
| Accepted name: |
sucrose-phosphate phosphatase |
| Reaction: |
sucrose 6F-phosphate + H2O = sucrose + phosphate |
| Other name(s): |
sucrose 6-phosphate hydrolase; sucrose-phosphate hydrolase; sucrose-phosphate phosphohydrolase; sucrose-6-phosphatase; sucrose phosphatase; sucrose-6-phosphate phosphatase; SPP |
| Systematic name: |
sucrose-6F-phosphate phosphohydrolase |
| Comments: |
Requires Mg2+ for maximal activity [2]. This is the final step in the sucrose-biosynthesis pathway. The enzyme is highly specific for sucrose 6-phosphate, with fructose 6-phosphate unable to act as a substrate [2]. Belongs in the haloacid dehydrogenase (HAD) superfamily. The F of sucrose 6F-phosphate is used to indicate that the fructose residue of sucrose carries the substituent. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9059-33-0 |
| References: |
| 1. |
Hawker, J.S. and Hatch, M.D. A specific sucrose phosphatase from plant tissues. Biochem. J. 99 (1966) 102–107. [PMID: 4290548] |
| 2. |
Lunn, J.E., Ashton, A.R., Hatch, M.D. and Heldt, H.W. Purification, molecular cloning, and sequence analysis of sucrose-6F-phosphate phosphohydrolase from plants. Proc. Natl. Acad. Sci. USA 97 (2000) 12914–12919. [DOI] [PMID: 11050182] |
| 3. |
Lunn, J.E. and MacRae, E. New complexities in the synthesis of sucrose. Curr. Opin. Plant Biol. 6 (2003) 208–214. [DOI] [PMID: 12753969] |
| 4. |
Fieulaine, S., Lunn, J.E., Borel, F. and Ferrer, J.L. The structure of a cyanobacterial sucrose-phosphatase reveals the sugar tongs that release free sucrose in the cell. Plant Cell 17 (2005) 2049–2058. [DOI] [PMID: 15937230] |
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| [EC 3.1.3.24 created 1972, modified 2008] |
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