| EC |
3.1.21.2 |
| Accepted name: |
deoxyribonuclease IV (phage-T4-induced) |
| Reaction: |
Endonucleolytic cleavage to 5′-phosphooligonucleotide end-products |
| Other name(s): |
endodeoxyribonuclease IV (phage T4-induced); E. coli endonuclease IV; endodeoxyribonuclease (misleading); redoxyendonuclease; deoxriboendonuclease (misleading); Escherichia coli endonuclease II; endonuclease II; DNA-adenine-transferase |
| Comments: |
Preference for single-stranded DNA. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, METACYC, PDB, CAS registry number: 63363-78-0 |
| References: |
| 1. |
Friedberg, E.C. and Goldthwait, D.A. Endonuclease II of E. coli. I. Isolation and purification. Proc. Natl. Acad. Sci. USA 62 (1969) 934–940. [PMID: 4895219] |
| 2. |
Friedberg, E.C., Hadi, S.-M. and Goldthwait, D.A. Endonuclease II of Escherichia coli. II. Enzyme properties and studies on the degradation of alkylated and native deoxyribonucleic acid. J. Biol. Chem. 244 (1969) 5879–5889. [PMID: 4981786] |
| 3. |
Hadi, S.M. and Goldthwait, D.A. Endonuclease II of Escherichia coli. Degradation of partially depurinated deoxyribonucleic acid. Biochemistry 10 (1971) 4986–4993. [PMID: 4944066] |
| 4. |
Sadowski, P.D. and Hurwitz, J. Enzymatic breakage of deoxyribonucleic acid. I. Purification and properties of endonuclease II from T4 phage-infected Escherichia coli. J. Biol. Chem. 244 (1969) 6182–6191. [PMID: 4310836] |
|
| [EC 3.1.21.2 created 1972 as EC 3.1.4.30, transferred 1978 to EC 3.1.21.2] |
| |
|
| |
|
Printable version