EC |
3.1.13.2 |
Accepted name: |
exoribonuclease H |
Reaction: |
3′-end directed exonucleolytic cleavage of viral RNA-DNA hybrid |
Comments: |
This is a secondary reaction to the RNA 5′-end directed cleavage 13-19 nucleotides from the RNA end performed by EC 3.1.26.13 (retroviral ribonuclease H). |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
References: |
1. |
Schatz, O., Mous, J. and Le Grice, S.F. HIV-1 RT-associated ribonuclease H displays both endonuclease and 3′—5′ exonuclease activity. EMBO J. 9 (1990) 1171–1176. [PMID: 1691093] |
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[EC 3.1.13.2 created 1978, modified 2010] |
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