The Enzyme Database

Your query returned 11 entries.    printer_iconPrintable version



EC 3.1.1.4     
Accepted name: phospholipase A2
Reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate
Other name(s): lecithinase A; phosphatidase; phosphatidolipase; phospholipase A
Systematic name: phosphatidylcholine 2-acylhydrolase
Comments: Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position. Requires Ca2+.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9001-84-7
References:
1.  Doery, H.M. and Pearson, J.E. Haemolysins in venoms of Australian snakes. Observations on the haemolysins of the venoms of some Australian snakes and the separation of phospholipase A from the venom of Pseudechis porphyriacus. Biochem. J. 78 (1961) 820–827. [PMID: 13723433]
2.  Fraenkel-Conrat, H. and Fraenkel-Conrat, J. Inactivation of crotoxin by group-specific reagents. Biochim. Biophys. Acta 5 (1950) 98–104. [DOI] [PMID: 15433984]
3.  Hanahan, D.J., Brockerhoff, H. and Barron, E.J. The site of attack of phospholipase (lecithinase) A on lecithin: a re-evaluation. Position of fatty acids on lecithins and triglycerides. J. Biol. Chem. 235 (1960) 1917–1923. [PMID: 14399412]
4.  Moore, J.H. and Williams, D.L. Some observations on the specificity of phospholipase A. Biochim. Biophys. Acta 84 (1964) 41–54. [PMID: 14124755]
5.  Saito, K. and Hanahan, D.J. A study of the purification and properties of the phospholipase A of Crotalus adamanteus venom. Biochemistry 1 (1962) 521–532. [PMID: 14496116]
6.  van den Bosch, H. Intracellular phospholipases A. Biochim. Biophys. Acta 604 (1980) 191–246. [DOI] [PMID: 6252969]
[EC 3.1.1.4 created 1961, modified 1976, modified 1983]
 
 
EC 3.1.1.40     
Accepted name: orsellinate-depside hydrolase
Reaction: orsellinate depside + H2O = 2 orsellinate
Glossary: orsellinate = 2,4-dihydroxy-6-methylbenzoate
Other name(s): lecanorate hydrolase
Systematic name: orsellinate-depside hydrolase
Comments: The enzyme will only hydrolyse those substrates based on the 2,4-dihydroxy-6-methylbenzoate structure that also have a free hydroxy group ortho to the depside linkage.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 62213-12-1
References:
1.  Schultz, J. and Mosbach, K. Studies on lichen enzymes. Purification and properties of an orsellinate depside hydrolase obtained from Lasallia pustulata. Eur. J. Biochem. 22 (1971) 153–157. [DOI] [PMID: 5116606]
[EC 3.1.1.40 created 1976]
 
 
EC 3.1.1.41     
Accepted name: cephalosporin-C deacetylase
Reaction: cephalosporin C + H2O = deacetylcephalosporin C + acetate
For diagram of cephalosporin biosynthesis, click here
Other name(s): cephalosporin C acetyl-hydrolase; cephalosporin C acetylase; cephalosporin acetylesterase; cephalosporin C acetylesterase; cephalosporin C acetyl-esterase; cephalosporin C deacetylase
Systematic name: cephalosporin-C acetylhydrolase
Comments: Hydrolyses the acetyl ester bond on the 10-position of the antibiotic cephalosporin C.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 52227-71-1
References:
1.  Fujisawa, Y., Shirafuji, H., Kida, M. and Nara, K. New findings on cephalosporin C biosynthesis. Nat. New Biol. 246 (1973) 154–155. [PMID: 4519146]
[EC 3.1.1.41 created 1976]
 
 
EC 3.1.1.42     
Accepted name: chlorogenate hydrolase
Reaction: chlorogenate + H2O = caffeate + quinate
Other name(s): chlorogenase; chlorogenic acid esterase
Systematic name: chlorogenate hydrolase
Comments: Also acts, more slowly, on isochlorogenate. No other substrates are known.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 74082-59-0
References:
1.  Schöbel, B. and Pollmann, W. Isolation and characterization of a chlorogenic acid esterase from Aspergillus niger. Z. Naturforsch. C: Biosci. 35 (1980) 209–212. [PMID: 7385941]
2.  Schöbel, B. and Pollmann, W. Weitere Charakterisierung einer Chlorogensäure - Hydrolase aus Aspergillus niger. Z. Naturforsch. C: Biosci. 35 (1980) 699–701. [PMID: 7445677]
[EC 3.1.1.42 created 1981]
 
 
EC 3.1.1.43     
Accepted name: α-amino-acid esterase
Reaction: an α-amino acid ester + H2O = an α-amino acid + an alcohol
Other name(s): α-amino acid ester hydrolase
Systematic name: α-amino-acid-ester aminoacylhydrolase
Comments: Also catalyses α-aminoacyl transfer to a number of amine nucleophiles.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 74506-40-4
References:
1.  Kato, K., Kawahara, K., Takahashi, T. and Kakinuma, A. Purification of an α-amino acid ester hydrolase from Xanthomonas citri. Agric. Biol. Chem. 44 (1980) 1069–1074.
2.  Kato, K., Kawahara, K., Takahashi, T. and Kakinuma, A. Substrate specificity of an α-amino acid ester hydrolase from Xanthomonas citri. Agric. Biol. Chem. 44 (1980) 1075–1081.
3.  Takahashi, T., Yamazaki, Y. and Kato, K. Substrate specificity of an α-amino acid ester hydrolase produced by Acetobacter turbidans A. T.C.C. 9325. Biochem. J. 137 (1974) 497–503. [PMID: 4424889]
[EC 3.1.1.43 created 1983]
 
 
EC 3.1.1.44     
Accepted name: 4-methyloxaloacetate esterase
Reaction: oxaloacetate 4-methyl ester + H2O = oxaloacetate + methanol
Systematic name: oxaloacetate-4-methyl-ester oxaloacetohydrolase
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 74812-46-7
References:
1.  Donnelly, M.I. and Dagley, S. Production of methanol from aromatic acids by Pseudomonas putida. J. Bacteriol. 142 (1980) 916–924. [PMID: 7380811]
[EC 3.1.1.44 created 1983]
 
 
EC 3.1.1.45     
Accepted name: carboxymethylenebutenolidase
Reaction: 4-carboxymethylenebut-2-en-4-olide + H2O = 4-oxohex-2-enedioate
Other name(s): maleylacetate enol-lactonase; dienelactone hydrolase; carboxymethylene butenolide hydrolase
Systematic name: 4-carboxymethylenebut-2-en-4-olide lactonohydrolase
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, UM-BBD, CAS registry number: 76689-22-0
References:
1.  Schmidt, E. and Knackmuss, H.-J. Chemical structure and biodegradability of halogenated aromatic compounds. Conversion of chlorinated muconic acids into maleoylacetic acid. Biochem. J. 192 (1980) 339–347. [PMID: 7305906]
[EC 3.1.1.45 created 1983]
 
 
EC 3.1.1.46     
Accepted name: deoxylimonate A-ring-lactonase
Reaction: deoxylimonate + H2O = deoxylimononic acid D-ring-lactone
Systematic name: deoxylimonate A-ring-lactonohydrolase
Comments: The enzyme opens the A-ring-lactone of the triterpenoid deoxylimonic acid, leaving the D-ring-lactone intact.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 75788-82-8
References:
1.  Hasegawa, H., Bennett, R.D. and Verdon, C.P. Metabolism of limonoids via a deoxylimonoid pathway in Citrus. Phytochemistry 19 (1980) 1445–1447.
[EC 3.1.1.46 created 1983]
 
 
EC 3.1.1.47     
Accepted name: 1-alkyl-2-acetylglycerophosphocholine esterase
Reaction: 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-alkyl-sn-glycero-3-phosphocholine + acetate
Other name(s): 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetylhydrolase; alkylacetyl-GPC:acetylhydrolase
Systematic name: 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 76901-00-3
References:
1.  Blank, M.L., Lee, T.-C., Fitzgerald, V. and Snyder, F. A specific acetylhydrolase for 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (a hypotensive and platelet-activating lipid). J. Biol. Chem. 256 (1981) 175–178. [PMID: 7451433]
[EC 3.1.1.47 created 1984]
 
 
EC 3.1.1.48     
Accepted name: fusarinine-C ornithinesterase
Reaction: N5-acyl-L-ornithine ester + H2O = N5-acyl-L-ornithine + an alcohol
Other name(s): ornithine esterase; 5-N-acyl-L-ornithine-ester hydrolase
Systematic name: N5-acyl-L-ornithine-ester hydrolase
Comments: Hydrolyses the three ornithine ester bonds in fusarinine C. Also acts on N5-dinitrophenyl-L-ornithine methyl ester.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 60202-10-0
References:
1.  Emery, T. Fungal ornithine esterases: relationship to iron transport. Biochemistry 15 (1976) 2723–2728. [PMID: 949472]
[EC 3.1.1.48 created 1984]
 
 
EC 3.1.1.49     
Accepted name: sinapine esterase
Reaction: sinapoylcholine + H2O = sinapate + choline
Other name(s): aromatic choline esterase
Systematic name: sinapoylcholine sinapohydrolase
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 72506-67-3
References:
1.  Nurmann, G. and Strack, D. Sinapine esterase. 1. Characterization of sinapine esterase from cotyledons of Raphanus sativus. Z. Naturforsch. C: Biosci. 34 (1979) 715–720.
[EC 3.1.1.49 created 1984]
 
 


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