| EC |
2.8.3.6 |
| Accepted name: |
3-oxoadipate CoA-transferase |
| Reaction: |
succinyl-CoA + 3-oxoadipate = succinate + 3-oxoadipyl-CoA |
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For diagram of benzoate metabolism, click here and for diagram of 4-nitrophenol metabolism, click here |
| Other name(s): |
3-oxoadipate coenzyme A-transferase; 3-oxoadipate succinyl-CoA transferase |
| Systematic name: |
succinyl-CoA:3-oxoadipate CoA-transferase |
| Comments: |
The enzyme, often found in soil bacteria and fungi, is involved in the catabolism of a variety of aromatic compounds, including catechol and protocatechuate, which are degraded via 3-oxoadipate. |
| Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9026-16-8 |
| References: |
| 1. |
Katagiri, M. and Hayaishi, O. Enzymatic degradation of β-ketoadipic acid. J. Biol. Chem. 226 (1957) 439–448. [PMID: 13428776] |
| 2. |
Kaschabek, S.R., Kuhn, B., Müller, D., Schmidt, E. and Reineke, W. Degradation of aromatics and chloroaromatics by Pseudomonas sp. strain B13: purification and characterization of 3-oxoadipate:succinyl-coenzyme A (CoA) transferase and 3-oxoadipyl-CoA thiolase. J. Bacteriol. 184 (2002) 207–215. [DOI] [PMID: 11741862] |
| 3. |
Gobel, M., Kassel-Cati, K., Schmidt, E. and Reineke, W. Degradation of aromatics and chloroaromatics by Pseudomonas sp. strain B13: cloning, characterization, and analysis of sequences encoding 3-oxoadipate:succinyl-coenzyme A (CoA) transferase and 3-oxoadipyl-CoA thiolase. J. Bacteriol. 184 (2002) 216–223. [DOI] [PMID: 11741863] |
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| [EC 2.8.3.6 created 1961] |
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