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Your query returned 1 entry. 
Printable version
| EC | 2.8.2.31 | ||
| Accepted name: | petromyzonol sulfotransferase | ||
| Reaction: | 3′-phosphoadenylyl sulfate + 5α-cholan-3α,7α,12α,24-tetrol = adenosine 3′,5′-bisphosphate + 5α-cholan-3α,7α,12α-triol 24-sulfate | ||
| For diagram of reaction, click here | |||
| Glossary: | petromyzonol = 5α-cholan-3α,7α,12α,24-tetrol 3′-phosphoadenylyl sulfate = PAPS |
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| Other name(s): | PZ-SULT; 3′-phosphoadenylyl-sulfate:5α-cholan-3α,7α,12α,24-tetrol sulfotransferase | ||
| Systematic name: | 3′-phosphoadenylyl-sulfate:5α-cholan-3α,7α,12α,24-tetrol sulfonotransferase | ||
| Comments: | The enzyme from the lamprey Petromyzon marinus can also use the corresponding 3-ketone as a substrate. It is stereoselective (5α-cholane) and regioselective, exhibiting a preference for an hydroxy group at C-24. The enzyme is inactive when allocholic acid, which has a carboxy group at C-24, is used as a substrate. | ||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||
| References: |
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