EC |
2.8.2.3 |
Accepted name: |
amine sulfotransferase |
Reaction: |
3′-phosphoadenylyl sulfate + an amine = adenosine 3′,5′-bisphosphate + a sulfamate |
Glossary: |
3′-phosphoadenylyl sulfate = PAPS |
Other name(s): |
arylamine sulfotransferase; amine N-sulfotransferase; 3′-phosphoadenylyl-sulfate:amine N-sulfotransferase |
Systematic name: |
3′-phosphoadenylyl-sulfate:amine N-sulfonotransferase |
Comments: |
A large number of primary and secondary amines can act as acceptors, including aniline, 2-naphthylamine, cyclohexylamine and octylamine. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9026-08-8 |
References: |
1. |
Ramaswamy, S.G. and Jakoby, W.B. Amine N-sulfotransferase. J. Biol. Chem. 262 (1987) 10039–10043. [PMID: 3475273] |
2. |
Roy, A.B. The enzymic synthesis of aryl sulphamates. Biochem. J. 74 (1960) 49–56. [PMID: 14439731] |
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[EC 2.8.2.3 created 1965] |
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