The Enzyme Database

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EC 2.8.2.21     
Accepted name: keratan sulfotransferase
Reaction: 3′-phosphoadenylyl sulfate + keratan = adenosine 3′,5′-bisphosphate + keratan 6′-sulfate
Glossary: 3′-phosphoadenylyl sulfate = PAPS
Other name(s): 3′-phosphoadenylyl keratan sulfotransferase; keratan sulfate sulfotransferase; 3′-phosphoadenylylsulfate:keratan sulfotransferase
Systematic name: 3′-phosphoadenylyl-sulfate:keratan 6′-sulfotransferase
Comments: Sulfation takes place at the 6-position of galactosyl and N-acetylglucosaminyl residues in keratan, a proteoglycan. Not identical with EC 2.8.2.5 (chondroitin 4-sulfotransferase), EC 2.8.2.6 (choline sulfotransferase) or EC 2.8.2.17 (chondroitin 6-sulfotransferase).
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 62168-79-0
References:
1.  Ruter, E.-R. and Kresse, H. Partial purification and characterization of 3′-phosphoadenylylsulfate:keratan sulfate sulfotransferases. J. Biol. Chem. 259 (1984) 11771–11776. [PMID: 6592165]
[EC 2.8.2.21 created 1989]
 
 


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