The Enzyme Database

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EC 2.8.2.18     
Accepted name: cortisol sulfotransferase
Reaction: 3′-phosphoadenylyl sulfate + cortisol = adenosine 3′,5′-bisphosphate + cortisol 21-sulfate
Glossary: 3′-phosphoadenylyl sulfate = PAPS
Other name(s): glucocorticosteroid sulfotransferase; glucocorticoid sulfotransferase
Systematic name: 3′-phosphoadenylyl-sulfate:cortisol 21-sulfotransferase
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 59782-20-6
References:
1.  Singer, S.S. and Brill, B. Enzymatic sulfation of steroids. XVII. The properties of the glucocorticoid sulfotransferase activity of guinea pig liver cytosol. Biochim. Biophys. Acta 712 (1982) 590–596. [PMID: 6957246]
2.  Singer, S.S., Giera, D., Johnson, J. and Sylvester, S. Enzymatic sulfation of steroids: I. The enzymatic basis for the sex difference in cortisol sulfation by rat liver preparations. Endocrinology 98 (1976) 963–974. [PMID: 1278101]
[EC 2.8.2.18 created 1986]
 
 


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