EC |
2.8.2.15 |
Accepted name: |
steroid sulfotransferase |
Reaction: |
3′-phosphoadenylyl sulfate + a phenolic steroid = adenosine 3′,5′-bisphosphate + steroid O-sulfate |
Glossary: |
3′-phosphoadenylyl sulfate = PAPS |
Other name(s): |
steroid alcohol sulfotransferase; 3′-phosphoadenylyl-sulfate:phenolic-steroid sulfotransferase |
Systematic name: |
3′-phosphoadenylyl-sulfate:phenolic-steroid sulfonotransferase |
Comments: |
Broad specificity resembling EC 2.8.2.2 alcohol sulfotransferase, but also acts on estrone. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 9032-76-2 |
References: |
1. |
Adams, J.B. and McDonald, D. Enzymic synthesis of steroid sulphates. XIII. Isolation and properties of dehydroepiandrosterone sulphotransferase from human foetal adrenals. Biochim. Biophys. Acta 615 (1980) 275–278. [DOI] [PMID: 6932974] |
|
[EC 2.8.2.15 created 1984] |
|
|
|
|