The Enzyme Database

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EC 2.8.2.15     
Accepted name: steroid sulfotransferase
Reaction: 3′-phosphoadenylyl sulfate + a phenolic steroid = adenosine 3′,5′-bisphosphate + steroid O-sulfate
Glossary: 3′-phosphoadenylyl sulfate = PAPS
Other name(s): steroid alcohol sulfotransferase; 3′-phosphoadenylyl-sulfate:phenolic-steroid sulfotransferase
Systematic name: 3′-phosphoadenylyl-sulfate:phenolic-steroid sulfonotransferase
Comments: Broad specificity resembling EC 2.8.2.2 alcohol sulfotransferase, but also acts on estrone.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 9032-76-2
References:
1.  Adams, J.B. and McDonald, D. Enzymic synthesis of steroid sulphates. XIII. Isolation and properties of dehydroepiandrosterone sulphotransferase from human foetal adrenals. Biochim. Biophys. Acta 615 (1980) 275–278. [DOI] [PMID: 6932974]
[EC 2.8.2.15 created 1984]
 
 


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