The Enzyme Database

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EC 2.7.8.24     
Accepted name: phosphatidylcholine synthase
Reaction: CDP-diacylglycerol + choline = CMP + phosphatidylcholine
Other name(s): CDP-diglyceride-choline O-phosphatidyltransferase
Systematic name: CDP-diacylglycerol:choline O-phosphatidyltransferase
Comments: Requires divalent cations, with Mn2+ being more effective than Mg2+.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 243666-86-6
References:
1.  de Rudder, K.E.E., Sohlenkamp, C. and Geiger, O. Plant-exudated choline is used for rhizobial membrane lipid biosynthesis by phosphatidylcholine synthase. J. Biol. Chem. 274 (1999) 20011–20016. [PMID: 10391951]
2.  Sohlenkamp, C., de Rudder, K.E.E., Röhrs, V., López-Lara, I.M. and Geiger, O. Cloning and characterization of the gene for phosphatidylcholine synthase. J. Biol. Chem. 275 (2000) 18919–18925. [PMID: 10858449]
[EC 2.7.8.24 created 2001]
 
 


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