The Enzyme Database

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EC 2.7.7.71     
Accepted name: D-glycero-α-D-manno-heptose 1-phosphate guanylyltransferase
Reaction: D-glycero-α-D-manno-heptose 1-phosphate + GTP = GDP-D-glycero-α-D-manno-heptose + diphosphate
Other name(s): hddC (gene name); gmhD (gene name)
Systematic name: GTP:D-glycero-α-D-manno-heptose 1-phosphate guanylyltransferase
Comments: The enzyme is involved in biosynthesis of GDP-D-glycero-α-D-manno-heptose, which is required for assembly of S-layer glycoprotein in some Gram-positive bacteria.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Kneidinger, B., Graninger, M., Puchberger, M., Kosma, P. and Messner, P. Biosynthesis of nucleotide-activated D-glycero-D-manno-heptose. J. Biol. Chem. 276 (2001) 20935–20944. [PMID: 11279237]
[EC 2.7.7.71 created 2010]
 
 


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