ExplorEnz: EC 2.7.7.45

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2.7.7.45

Accepted name:

guanosine-triphosphate guanylyltransferase

Reaction:

2 GTP = diphosphate + P¹,P⁴-bis(5′-guanosyl) tetraphosphate

Other name(s):

diguanosine tetraphosphate synthetase; GTP-GTP guanylyltransferase; Gp4G synthetase; guanosine triphosphate-guanose triphosphate guanylyltransferase

Systematic name:

GTP:GTP guanylyltransferase

Comments:

Also acts, more slowly, on GDP to form P¹,P³-bis(5′-guanosyl) triphosphate.

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 54576-89-5

References:

1.	Warner, A.H., Beers, P.C. and Huang, F.L. Biosynthesis of the diguanosine nucleotides. I. Purification and properties of an enzyme from yolk platelets of brine shrimp embryos. Can. J. Biochem. 52 (1974) 231–240. [PMID: 4208243]

[EC 2.7.7.45 created 1976]