The Enzyme Database

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EC 2.7.7.43     
Accepted name: N-acylneuraminate cytidylyltransferase
Reaction: CTP + N-acylneuraminate = diphosphate + CMP-N-acylneuraminate
For diagram of N-Acetylneuraminic acid biosynthesis, click here
Other name(s): CMP-sialate pyrophosphorylase; CMP-sialate synthase; cytidine 5′-monophosphosialic acid synthetase; CMP-Neu5Ac synthetase; CMP-NeuAc synthetase; acylneuraminate cytidyltransferase; CMP-N-acetylneuraminate synthetase; CMP-N-acetylneuraminate synthase; CMP-N-acetylneuraminic acid synthase; CMP-NANA synthetase; CMP-sialate synthetase; CMP-sialic synthetase; cytidine 5′-monophospho-N-acetylneuraminic acid synthetase; cytidine 5-monophosphate N-acetylneuraminic acid synthetase; cytidine monophosphosialic acid synthetase; cytidine monophosphoacetylneuraminic synthetase; cytidine monophosphosialate pyrophosphorylase; cytidine monophosphosialate synthetase; acetylneuraminate cytidylyltransferase
Systematic name: CTP:N-acylneuraminate cytidylyltransferase
Comments: Acts on N-acetyl- and N-glycolyl- derivatives.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9067-82-7
References:
1.  Kean, E.L. and Roseman, S. The sialic acids. X. Purification and properties of cytidine 5′-monophosphosialic acid synthetase. J. Biol. Chem. 241 (1966) 5643–5650. [PMID: 4288894]
[EC 2.7.7.43 created 1972]
 
 


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