| EC |
2.7.7.28 |
| Accepted name: |
nucleoside-triphosphate-aldose-1-phosphate nucleotidyltransferase |
| Reaction: |
nucleoside triphosphate + α-D-aldose 1-phosphate = diphosphate + NDP-hexose |
| Other name(s): |
NDP hexose pyrophosphorylase; hexose 1-phosphate nucleotidyltransferase; hexose nucleotidylating enzyme; nucleoside diphosphohexose pyrophosphorylase; hexose-1-phosphate guanylyltransferase; GTP:α-D-hexose-1-phosphate guanylyltransferase; GDP hexose pyrophosphorylase; guanosine diphosphohexose pyrophosphorylase; nucleoside-triphosphate-hexose-1-phosphate nucleotidyltransferase; NTP:hexose-1-phosphate nucleotidyltransferase |
| Systematic name: |
NTP:α-D-aldose-1-phosphate nucleotidyltransferase |
| Comments: |
In decreasing order of activity, guanosine, inosine and adenosine diphosphate hexoses are substrates in the reverse reaction, with either glucose or mannose as the sugar. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 37278-26-5 |
| References: |
| 1. |
Verachtert, H., Rodriguez, P., Bass, S.T. and Hansen, R.G. Purification and properties of guanosine diphosphate hexose pyrophosphorylase from mammalian tissues. J. Biol. Chem. 241 (1966) 2007–2013. [PMID: 5946626] |
| 2. |
Hansen, R.G., Verachtert, H., Rodriguez, P. and Bass, S.T. GDP-hexose pyrophosphorylase from liver. Methods Enzymol. 8 (1966) 269–271. |
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| [EC 2.7.7.28 created 1972, modified 2004 (EC 2.7.7.29 created 1972, incorporated 2004)] |
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