The Enzyme Database

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Accepted name: protein-histidine pros-kinase
Reaction: ATP + protein L-histidine = ADP + protein Nπ-phospho-L-histidine
Other name(s): ATP:protein-L-histidine N-pros-phosphotransferase; histidine kinase (ambiguous); histidine protein kinase (ambiguous); protein histidine kinase (ambiguous); protein kinase (histidine) (ambiguous); HK2
Systematic name: ATP:protein-L-histidine Nπ-phosphotransferase
Comments: A number of histones can act as acceptor.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 99283-67-7
1.  Fujitaki, J.M., Fung, G., Oh, E.Y. and Smith, R.A. Characterization of chemical and enzymatic acid-labile phosphorylation of histone H4 using phosphorus-31 nuclear magnetic resonance. Biochemistry 20 (1981) 3658–3664. [PMID: 7196259]
2.  Huebner, V.D. and Matthews, H.R. Phosphorylation of histidine in proteins by a nuclear extract of Physarum polycephalum plasmodia. J. Biol. Chem. 260 (1985) 16106–16113. [PMID: 4066704]
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