| EC |
2.7.11.28 |
| Accepted name: |
tropomyosin kinase |
| Reaction: |
ATP + tropomyosin = ADP + O-phosphotropomyosin |
| Other name(s): |
tropomyosin kinase (phosphorylating); STK (ambiguous) |
| Systematic name: |
ATP:tropomyosin O-phosphotransferase |
| Comments: |
The enzyme phosphorylates casein equally well, and histone and phosvitin to a lesser extent. The acceptor is a serine residue in the protein. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 90804-56-1 |
| References: |
| 1. |
deBelle, I. and Mak, A.S. Isolation and characterization of tropomyosin kinase from chicken embryo. Biochim. Biophys. Acta 925 (1987) 17–26. [DOI] [PMID: 3593768] |
| 2. |
Montgomery, K. and Mak, A.S. In vitro phosphorylation of tropomyosin by a kinase from chicken embryo. J. Biol. Chem. 259 (1984) 5555–5560. [PMID: 6325440] |
| 3. |
Watson, M.H., Taneja, A.K., Hodges, R.S. and Mak, A.S. Phosphorylation of αα- and ββ-tropomyosin and synthetic peptide analogues. Biochemistry 27 (1988) 4506–4512. [PMID: 3166994] |
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| [EC 2.7.11.28 created 1990 as EC 2.7.1.132, transferred 2005 to EC 2.7.11.28] |
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