Deoxyuridine can also act as acceptor, and dGTP can act as a donor. The deoxypyrimidine kinase complex induced by Herpes simplex virus catalyses this reaction as well as those of EC 188.8.131.52 (AMP—thymidine kinase), EC 184.108.40.206 (ADP—thymidine kinase) and EC 220.127.116.11 (dTMP-kinase).
Falke, D., Labenz, J., Brauer, D. and Muller, W.E.G. Adenosine diphosphate: thymidine 5′-phosphotransferase, a new enzyme activity, associated with the Herpes simplex virus-induced deoxypyrimidine kinase. Biochim. Biophys. Acta708 (1982) 99–103. [DOI] [PMID: 6293576]
Kizer, D.E. and Holman, L. Purification and properties of thymidine kinase from regenerating rat liver. Biochim. Biophys. Acta350 (1974) 193–200. [DOI] [PMID: 4407348]
Okazaki, R. and Kornberg, A. Deoxythymidine kinase of Escherichia coli. I. Purification and some properties of the enzyme. J. Biol. Chem.239 (1964) 269–274. [PMID: 14114853]
[EC 18.104.22.168 created 1961, deleted 1972, reinstated 1976 (EC 22.214.171.124 created 1972, incorporated 1976)]