The Enzyme Database

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EC 2.7.1.150     
Accepted name: 1-phosphatidylinositol-3-phosphate 5-kinase
Reaction: ATP + 1-phosphatidyl-1D-myo-inositol 3-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate
For diagram of 1-phosphatidyl-myo-inositol metabolism, click here
Glossary: 1-phosphatidyl-1D-myo-inositol 3-phosphate = PtdIns3P
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate = PtdIns(3,5)P2
Other name(s): type III PIP kinase; phosphatidylinositol 3-phosphate 5-kinase
Systematic name: ATP:1-phosphatidyl-1D-myo-inositol-3-phosphate 5-phosphotransferase
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Cooke, F.T., Dove, S.K., McEwen, R.K., Painter, G., Holmes, A.B., Hall, M.N., Michell, R.H. and Parker, P.J. The stress-activated phosphatidylinositol 3-phosphate 5-kinase Fab1p is essential for vacuole function in S. cerevisiae. Curr. Biol. 9 (1998) 1219–1222. [PMID: 9811604]
[EC 2.7.1.150 created 2002]
 
 


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