The Enzyme Database

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EC 2.7.1.149     
Accepted name: 1-phosphatidylinositol-5-phosphate 4-kinase
Reaction: ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
For diagram of 1-phosphatidyl-myo-inositol metabolism (part 2), click here
Glossary: 1-phosphatidyl-1D-myo-inositol 5-phosphate = PtdIns5P
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate = PtdIns(4,5)P2
Other name(s): type II PIP kinase
Systematic name: ATP:1-phosphatidyl-1D-myo-inositol-5-phosphate 4-phosphotransferase
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 247907-17-1
References:
1.  Rameh, L.E., Tolias, K.F., Duckworth, B.C. and Cantley, L.C. A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate. Nature 390 (1997) 192–196. [PMID: 9367159]
[EC 2.7.1.149 created 2002]
 
 


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