The Enzyme Database

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EC 2.7.1.136     
Accepted name: macrolide 2′-kinase
Reaction: ATP + oleandomycin = ADP + oleandomycin 2′-O-phosphate
Systematic name: ATP:macrolide 2′-O-phosphotransferase
Comments: Erythromycin, spiramycin and some other macrolide antibiotics can also act as acceptors.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 116036-69-2
References:
1.  O'Hara, K., Kanda, T. and Kono, M. Structure of a phosphorylated derivative of oleandomycin, obtained by reaction of oleandomycin with an extract of an erythromycin-resistant strain of Escherichia coli. J. Antibiot. 41 (1988) 823–827. [PMID: 3042731]
[EC 2.7.1.136 created 1992]
 
 


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