| EC |
2.6.1.44 |
| Accepted name: |
alanine—glyoxylate transaminase |
| Reaction: |
L-alanine + glyoxylate = pyruvate + glycine |
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For diagram of reaction, click here and for mechanism, click here |
| Other name(s): |
AGT; alanine-glyoxylate aminotransferase; alanine-glyoxylic aminotransferase; L-alanine-glycine transaminase |
| Systematic name: |
L-alanine:glyoxylate aminotransferase |
| Comments: |
A pyridoxal-phosphate protein. With one component of the animal enzyme, 2-oxobutanoate can replace glyoxylate. A second component also catalyses the reaction of EC 2.6.1.51 serine—pyruvate transaminase. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9015-67-2 |
| References: |
| 1. |
Noguchi, T., Okuno, E., Takada, Y., Minatogawa, Y., Okai, K. and Kido, R. Characteristics of hepatic alanine-glyoxylate aminotransferase in different mammalian species. Biochem. J. 169 (1978) 113–122. [PMID: 629740] |
| 2. |
Okuno, E., Minatogawa, Y. and Kido, R. Co-purification of alanine-glyoxylate aminotransferase with 2-aminobutyrate aminotransferase in rat kidney. Biochim. Biophys. Acta 715 (1982) 97–104. [DOI] [PMID: 6803844] |
| 3. |
Thompson, J.S. and Richardson, K.E. Isolation and characterization of an L-alanine: glyoxylate aminotransferase from human liver. J. Biol. Chem. 242 (1967) 3614–3619. [PMID: 6038488] |
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| [EC 2.6.1.44 created 1972, modified 1982] |
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