The Enzyme Database

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EC 2.6.1.23     
Accepted name: 4-hydroxyglutamate transaminase
Reaction: 4-hydroxy-L-glutamate + 2-oxoglutarate = 4-hydroxy-2-oxoglutarate + L-glutamate
For diagram of reaction, click here and for mechanism, click here
Other name(s): 4-hydroxyglutamate aminotransferase
Systematic name: 4-hydroxy-L-glutamate:2-oxoglutarate aminotransferase
Comments: Oxaloacetate can replace 2-oxoglutarate. This enzyme may be identical with EC 2.6.1.1 aspartate transaminase.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 37277-86-4
References:
1.  Goldstone, A. and Adams, E. Metabolism of γ-hydroxyglutamic acid. I. Conversion to α-hydroxy-γ-ketoglutarate by purified glutamic-aspartic transaminase to rat liver. J. Biol. Chem. 237 (1962) 3476–3485. [PMID: 13948827]
2.  Kuratomi, K., Fukunaga, K. and Kobayashi, Y. The metabolism of γ-hydroxyglutamate in rat liver. II. A transaminase concerned in γ-hydroxyglutamate metabolism. Biochim. Biophys. Acta 78 (1963) 629–636. [PMID: 14089443]
[EC 2.6.1.23 created 1972, modified 1982]
 
 


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