The Enzyme Database

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EC 2.6.1.118     
Accepted name: [amino-group carrier protein]-γ-(L-lysyl)-L-glutamate aminotransferase
Reaction: an [amino-group carrier protein]-C-terminal-[γ-(L-lysyl)-L-glutamate] + 2-oxoglutarate = an [amino-group carrier protein]-C-terminal-[N-(1-carboxy-5-oxopentyl)-L-glutamine] + L-glutamate
Other name(s): lysJ (gene name)
Systematic name: 2-oxoglutarate:[amino-group carrier protein]-C-terminal-[γ-(L-lysyl)-L-glutamate] aminotransferase
Comments: The enzyme participates in an L-lysine biosynthesis pathway in certain species of archaea and bacteria.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB
References:
1.  Miyazaki, J., Kobashi, N., Nishiyama, M. and Yamane, H. Functional and evolutionary relationship between arginine biosynthesis and prokaryotic lysine biosynthesis through α-aminoadipate. J. Bacteriol. 183 (2001) 5067–5073. [PMID: 11489859]
2.  Horie, A., Tomita, T., Saiki, A., Kono, H., Taka, H., Mineki, R., Fujimura, T., Nishiyama, C., Kuzuyama, T. and Nishiyama, M. Discovery of proteinaceous N-modification in lysine biosynthesis of Thermus thermophilus. Nat. Chem. Biol. 5 (2009) 673–679. [DOI] [PMID: 19620981]
[EC 2.6.1.118 created 2019]
 
 


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