| EC |
2.6.1.107 |
| Accepted name: |
β-methylphenylalanine transaminase |
| Reaction: |
(2S,3S)-3-methylphenylalanine + 2-oxoglutarate = (3S)-2-oxo-3-phenylbutanoate + L-glutamate |
| Glossary: |
(3S)-2-oxo-3-phenylbutanoate = (3S)-β-methyl-phenylpyruvate |
| Other name(s): |
TyrB |
| Systematic name: |
(2S,3S)-3-methylphenylalanine:2-oxoglutarate aminotransferase |
| Comments: |
Requires pyridoxal phosphate. Isolated from the bacterium Streptomyces hygroscopicus NRRL3085. It is involved in the biosynthesis of the glycopeptide antibiotic mannopeptimycin. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Huang, Y.T., Lyu, S.Y., Chuang, P.H., Hsu, N.S., Li, Y.S., Chan, H.C., Huang, C.J., Liu, Y.C., Wu, C.J., Yang, W.B. and Li, T.L. In vitro characterization of enzymes involved in the synthesis of nonproteinogenic residue (2S,3S)-β-methylphenylalanine in glycopeptide antibiotic mannopeptimycin. ChemBioChem 10 (2009) 2480–2487. [DOI] [PMID: 19731276] |
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| [EC 2.6.1.107 created 2014] |
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