The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

Accepted name: coumarin 8-geranyltransferase
Reaction: (1) geranyl diphosphate + umbelliferone = diphosphate + 8-geranylumbelliferone
(2) geranyl diphosphate + esculetin = diphosphate + 8-geranylesculetin
Glossary: geranyl diphosphate = (2E)-3,7-dimethylocta-2,6-dien-1-yl diphosphate
esculetin = 6,7-dihydroxy-1-benzopyran-2-one = 6,7-dihydroxycoumarin
umbelliferone = 7-hydroxy-1-benzopyran-2-one = 7-hydroxycoumarin
Other name(s): ClPT1
Systematic name: geranyl diphosphate:umbelliferone 8-geranyltransferase
Comments: The enzyme, characterized from the plant Citrus limon, is specific for geranyl diphosphate as a prenyl donor. It also has low activity with the coumarins 5,7-dihydroxycoumarin and 5-methoxy-7-hydroxycoumarin.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
1.  Munakata, R., Inoue, T., Koeduka, T., Karamat, F., Olry, A., Sugiyama, A., Takanashi, K., Dugrand, A., Froelicher, Y., Tanaka, R., Uto, Y., Hori, H., Azuma, J., Hehn, A., Bourgaud, F. and Yazaki, K. Molecular cloning and characterization of a geranyl diphosphate-specific aromatic prenyltransferase from lemon. Plant Physiol. 166 (2014) 80–90. [DOI] [PMID: 25077796]
[EC created 2017]

Data © 2001–2018 IUBMB
Web site © 2005–2018 Andrew McDonald