The Enzyme Database

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EC 2.5.1.122     
Accepted name: 4-O-dimethylallyl-L-tyrosine synthase
Reaction: dimethylallyl diphosphate + L-tyrosine = diphosphate + 4-O-dimethylallyl-L-tyrosine
Other name(s): SirD
Systematic name: dimethylallyl diphosphate:L-tyrosine 4-O-dimethylallyltransferase
Comments: The enzyme is involved in biosynthesis of the phytotoxin sirodesmin PL by the phytopathogenic ascomycete Leptosphaeria maculans.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Kremer, A. and Li, S.M. A tyrosine O-prenyltransferase catalyses the first pathway-specific step in the biosynthesis of sirodesmin PL. Microbiology 156 (2010) 278–286. [PMID: 19762440]
2.  Zou, H.X., Xie, X., Zheng, X.D. and Li, S.M. The tyrosine O-prenyltransferase SirD catalyzes O-, N-, and C-prenylations. Appl. Microbiol. Biotechnol. 89 (2011) 1443–1451. [PMID: 21038099]
[EC 2.5.1.122 created 2014]
 
 


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