The Enzyme Database

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EC 2.4.1.91     
Accepted name: flavonol 3-O-glucosyltransferase
Reaction: UDP-glucose + a flavonol = UDP + a flavonol 3-O-β-D-glucoside
For diagram of kaempferol biosynthesis, click here and for diagram of the biosynthesis of quercetin 3-O-glycoside derivatives, click here
Other name(s): GTI; uridine diphosphoglucose-flavonol 3-O-glucosyltransferase; UDP-glucose:flavonol 3-O-glucosyltransferase; UDPG:flavonoid-3-O-glucosyltransferase
Systematic name: UDP-glucose:flavonol 3-O-D-glucosyltransferase
Comments: Acts on a variety of flavonols, including quercetin and quercetin 7-O-glucoside. Different from EC 2.4.1.81 (flavone 7-O-β-glucosyltransferase).
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 50812-18-5
References:
1.  Kleinehollenhorst, G., Behrens, H., Pegels, G., Srunk, N. and Wiermann, R. Formation of flavonol 3-O-diglycosides and flavonol 3-O-triglycosides by enzyme extracts from anthers of Tulipa cv apeldoorn - characterization and activity of 3 different O-glycosyltransferases during anther development. Z. Natursforsch. C: Biosci. 37 (1982) 587–599.
2.  Sutter, A. and Grisebach, H. UDP-glucose: flavonol 3-O-glucosyltransferase from cell suspension cultures of parsley. Biochim. Biophys. Acta 309 (1973) 289–295. [PMID: 4731963]
[EC 2.4.1.91 created 1976]
 
 


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