The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

EC 2.4.1.80     
Accepted name: ceramide glucosyltransferase
Reaction: UDP-glucose + an N-acylsphingosine = UDP + a D-glucosyl-N-acylsphingosine
For diagram of glycolipid biosynthesis, click here. For diagram of reaction, click here
Other name(s): UDP-glucose:ceramide glucosyltransferase; ceramide:UDP-Glc glucosyltransferase; uridine diphosphoglucose-ceramide glucosyltransferase; ceramide:UDP-glucose glucosyltransferase; glucosylceramide synthase
Systematic name: UDP-glucose:N-acylsphingosine D-glucosyltransferase
Comments: Sphingosine and dihydrosphingosine can also act as acceptors; CDP-glucose can act as donor.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 37237-44-8
References:
1.  Basu, S., Kaufman, B. and Roseman, S. Enzymatic synthesis of glucocerebroside by a glucosyltransferase from embryonic chicken brain. J. Biol. Chem. 248 (1973) 1388–1394. [PMID: 4631392]
[EC 2.4.1.80 created 1976]
 
 


Data © 2001–2014 IUBMB
Web site © 2005–2014 Andrew McDonald