The Enzyme Database

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Accepted name: procollagen glucosyltransferase
Reaction: UDP-glucose + (2S,5R)-5-O-(β-D-galactosyl)-5-hydroxy-L-lysine-[procollagen] = UDP + (2S,5R)-5-O-[α-D-glucosyl-(1→2)-β-D-galactosyl]-5-hydroxy-L-lysine-[procollagen]
Other name(s): galactosylhydroxylysine glucosyltransferase; collagen glucosyltransferase; collagen hydroxylysyl glucosyltransferase; galactosylhydroxylysyl glucosyltransferase; UDP-glucose-collagenglucosyltransferase; uridine diphosphoglucose-collagen glucosyltransferase; UDP-glucose:5-(D-galactosyloxy)-L-lysine-procollagen D-glucosyltransferase
Systematic name: UDP-glucose:(2S,5R)-5-O-(β-D-galactosyl)-5-hydroxy-L-lysine-[procollagen] D-glucosyltransferase
Comments: Probably involved in the synthesis of carbohydrate units in complement (cf. EC procollagen galactosyltransferase).
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 9028-08-4
1.  Bosmann, H.B. and Eylar, E.H. Attachment of carbohydrate to collagen. Isolation, purification and properties of the glucosyl transferase. Biochem. Biophys. Res. Commun. 30 (1968) 89–94. [PMID: 5637038]
2.  Bosmann, H.B. and Eylar, E.H. Collagen-glucosyl transferase in fibriblasts transformed by oncogenic viruses. Nature 218 (1968) 582–583. [PMID: 4968368]
3.  Butler, W.T. and Cunningham, L.W. Evidence for the linkage of a disaccharide to hydroxylysine in tropocollagen. J. Biol. Chem. 241 (1966) 3882–3888. [PMID: 4288358]
4.  Kivirikko, K.I. and Myllyla, R. In: Hall, D.A. and Jackson, D.S. (Eds), International Review of Connective Tissue Research, vol. 8, Academic Press, New York, 1979, p. 23.
[EC created 1972]

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