The Enzyme Database

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EC 2.4.1.50     
Accepted name: procollagen galactosyltransferase
Reaction: UDP-α-D-galactose + procollagen 5-hydroxy-L-lysine = UDP + procollagen 5-(D-galactosyloxy)-L-lysine
Other name(s): hydroxylysine galactosyltransferase; collagen galactosyltransferase; collagen hydroxylysyl galactosyltransferase; UDP galactose-collagen galactosyltransferase; uridine diphosphogalactose-collagen galactosyltransferase; UDPgalactose:5-hydroxylysine-collagen galactosyltransferase; UDP-galactose:procollagen-5-hydroxy-L-lysine D-galactosyltransferase
Systematic name: UDP-α-D-galactose:procollagen-5-hydroxy-L-lysine D-galactosyltransferase
Comments: Probably involved in the synthesis of carbohydrate units in complement (cf. EC 2.4.1.66 procollagen glucosyltransferase).
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 9028-07-3
References:
1.  Bosmann, H.B. and Eylar, E.H. Glycoprotein biosynthesis: the biosynthesis of the hydroxylysine-galactose linkage in collagen. Biochem. Biophys. Res. Commun. 33 (1968) 340–346. [PMID: 5722225]
2.  Kivirikko, K.I. and Myllyla, R. In: Hall, D.A. and Jackson, D.S. (Eds), International Review of Connective Tissue Research, vol. 8, Academic Press, New York, 1979, p. 23.
[EC 2.4.1.50 created 1972, modified 1983]
 
 


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