| EC |
2.4.1.45 |
| Accepted name: |
2-hydroxyacylsphingosine 1-β-galactosyltransferase |
| Reaction: |
UDP-α-D-galactose + a 2-(2-hydroxyacyl)sphingosine = UDP + a 1-(β-D-galactosyl)-2-(2-hydroxyacyl)sphingosine |
| Other name(s): |
uridine diphosphogalactose-2-hydroxyacylsphingosine galactosyltransferase; UDPgalactose-2-hydroxyacylsphingosine galactosyltransferase; UDP-galactose:ceramide galactosyltransferase; UDP-galactose:2-2-hydroxyacylsphingosine galactosyltransferase; UDP-galactose:2-(2-hydroxyacyl)sphingosine 1-β-D-galactosyl-transferase |
| Systematic name: |
UDP-α-D-galactose:2-(2-hydroxyacyl)sphingosine 1-β-D-galactosyl-transferase |
| Comments: |
Highly specific. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, METACYC, CAS registry number: 37277-54-6 |
| References: |
| 1. |
Basu, S., Schultz, A., Basu, M. and Roseman, S. Enzymatic synthesis of galactocerebroside by a galactosyltransferase from embryonic chicken brain. J. Biol. Chem. 243 (1971) 4272–4279. [PMID: 5090043] |
| 2. |
Morell, P. and Radin, N.S. Synthesis of cerebroside by brain from uridine diphosphate galactose and ceramide containing hydroxy fatty acid. Biochemistry 8 (1969) 506–512. [PMID: 5793706] |
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| [EC 2.4.1.45 created 1972] |
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