The Enzyme Database

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EC 2.4.1.298     
Accepted name: anthocyanidin 3-O-glucoside 5-O-glucosyltransferase
Reaction: UDP-α-D-glucose + an anthocyanidin 3-O-β-D-glucoside = UDP + an anthocyanidin 3,5-di-O-β-D-glucoside
For diagram of anthocyanidin glucoside biosynthesis, click here
Other name(s): UDP-glucose:anthocyanin 5-O-glucosyltransferase
Systematic name: UDP-α-D-glucose:anthocyanidin-3-O-β-D-glucoside 5-O-glucosyltransferase
Comments: Isolated from the plants Perilla frutescens var. crispa, Verbena hybrida [1], Dahlia variabilis [2] and Gentiana triflora (clustered gentian) [3]. It will also act on anthocyanidin 3-O-(6-O-malonylglucoside) [2] and is much less active with hydroxycinnamoylglucose derivatives [3]. There is no activity in the absence of the 3-O-glucoside group.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Yamazaki, M., Gong, Z., Fukuchi-Mizutani, M., Fukui, Y., Tanaka, Y., Kusumi, T. and Saito, K. Molecular cloning and biochemical characterization of a novel anthocyanin 5-O-glucosyltransferase by mRNA differential display for plant forms regarding anthocyanin. J. Biol. Chem. 274 (1999) 7405–7411. [PMID: 10066805]
2.  Ogata, J., Sakamoto, T., Yamaguchi, M., Kawanobu, S., Yoshitama, K. Isolation and characterization of anthocyanin 5-O-glucosyltransferase from flowers of Dahlia variabilis. J. Plant Physiol. 158 (2001) 709–714.
3.  Nakatsuka, T., Sato, K., Takahashi, H., Yamamura, S. and Nishihara, M. Cloning and characterization of the UDP-glucose:anthocyanin 5-O-glucosyltransferase gene from blue-flowered gentian. J. Exp. Bot. 59 (2008) 1241–1252. [PMID: 18375606]
[EC 2.4.1.298 created 2013]
 
 


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