The Enzyme Database

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Accepted name: cellulose synthase (GDP-forming)
Reaction: GDP-glucose + [(1→4)-β-D-glucosyl]n = GDP + [(1→4)-β-D-glucosyl]n+1
Other name(s): cellulose synthase (guanosine diphosphate-forming); cellulose synthetase; guanosine diphosphoglucose-1,4-β-glucan glucosyltransferase; guanosine diphosphoglucose-cellulose glucosyltransferase; GDP-glucose:1,4-β-D-glucan 4-β-D-glucosyltransferase
Systematic name: GDP-glucose:(1→4)-β-D-glucan 4-β-D-glucosyltransferase
Comments: Involved in the synthesis of cellulose. A similar enzyme [EC, cellulose synthase (UDP-forming)] utilizes UDP-glucose.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 9027-18-3
1.  Chambers, J.C. and Elbein, A.D. Biosynthesis of glucans in mung bean seedlings. Formation of β-(1,4)-glucans from GDP-glucose and β-(1,3)-glucans from UDP-glucose. Arch. Biochem. Biophys. 138 (1970) 620–631. [PMID: 4317490]
2.  Flowers, H.M., Batra, K.K., Kemp, J. and Hassid, W.Z. Biosynthesis of cellulose in vitro from guanosine diphosphate D-glucose with enzymic preparations from Phaseolus aureus and Lupinus albus. J. Biol. Chem. 244 (1969) 4969. [PMID: 5824571]
[EC created 1965]

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