The Enzyme Database

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EC 2.4.1.197     
Accepted name: high-mannose-oligosaccharide β-1,4-N-acetylglucosaminyltransferase
Reaction: Transfers an N-acetyl-D-glucosamine residue from UDP-N-acetyl-D-glucosamine to the 4-position of a mannose linked α-(1→6) to the core mannose of high-mannose oligosaccharides produced by Dictyostelium discoideum
Other name(s): uridine diphosphoacetylglucosamine-oligosaccharide acetylglucosaminyltransferase; acetylglucosamine-oligosaccharide acetylglucosaminyltransferase; UDP-GlcNAc:oligosaccharide β-N-acetylglucosaminyltransferase; UDP-N-acetyl-D-glucosamine:high-mannose-oligosaccharide β-1,4-N-acetylglucosaminyltransferase
Systematic name: UDP-N-acetyl-D-glucosamine:high-mannose-oligosaccharide 4-β-N-acetylglucosaminyltransferase
Comments: The activity of the intersecting mannose residue as acceptor is dependent on two other mannose residues attached by α-1,3 and α-1,6 links.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 123425-54-7
References:
1.  Sharkey, D.J. and Kornfeld, R. Identification of an N-acetylglucosaminyltransferase in Dictyostelium discoideum that transfers an "intersecting" N-acetylglucosamine residue to high mannose oligosaccharides. J. Biol. Chem. 264 (1989) 10411–10419. [PMID: 2525124]
[EC 2.4.1.197 created 1992]
 
 


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