The Enzyme Database

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EC 2.4.1.142     
Accepted name: chitobiosyldiphosphodolichol β-mannosyltransferase
Reaction: GDP-mannose + chitobiosyldiphosphodolichol = GDP + β-(1→4)-D-mannosylchitobiosyldiphosphodolichol
For diagram of dolichyltetradecasaccharide biosynthesis, click here
Other name(s): guanosine diphosphomannose-dolichol diphosphochitobiose mannosyltransferase; GDP-mannose-dolichol diphosphochitobiose mannosyltransferase
Systematic name: GDP-mannose:chitobiosyldiphosphodolichol β-D-mannosyltransferase
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 83380-85-2
References:
1.  Sharma, C.B., Lehle, L. and Tanner, W. Solubilization and characterization of the initial enzymes of the dolichol pathway from yeast. Eur. J. Biochem. 126 (1982) 319–325. [PMID: 6215245]
2.  Takahashi, T., Honda, R. and Nishikawa, Y. Cloning of the human cDNA which can complement the defect of the yeast mannosyltransferase I-deficient mutant alg 1. Glycobiology 10 (2000) 321–327. [PMID: 10704531]
[EC 2.4.1.142 created 1984, modified 2001]
 
 


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