| EC |
2.4.1.119 |
| Accepted name: |
dolichyl-diphosphooligosaccharide—protein glycotransferase |
| Reaction: |
dolichyl diphosphooligosaccharide + protein L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by N-glycosyl linkage to protein L-asparagine |
| Other name(s): |
dolichyldiphosphooligosaccharide-protein glycosyltransferase; asparagine N-glycosyltransferase; dolichyldiphosphooligosaccharide-protein oligosaccharyltransferase; dolichylpyrophosphodiacetylchitobiose-protein glycosyltransferase; oligomannosyltransferase; oligosaccharide transferase; dolichyldiphosphoryloligosaccharide-protein oligosaccharyltransferase |
| Systematic name: |
dolichyl-diphosphooligosaccharide:protein-L-asparagine oligopolysaccharidotransferase |
| Comments: |
Transfers the glucosyl-mannosyl-glucosamine polysaccharide side-chains of glycoproteins to an asparagine residue in the sequence Asn-Xaa-Ser or Asn-Xaa-Thr in the nascent polypeptide chains of the protein moiety. |
| Links to other databases: |
BRENDA, EXPASY, IUBMB, KEGG, PDB, CAS registry number: 75302-32-8 |
| References: |
| 1. |
Das, R.C. and Heath, E.C. Dolichyldiphosphoryloligosaccharide-protein oligosaccharyltransferase; solubilization, purification, and properties. Proc. Natl. Acad. Sci. USA 77 (1980) 3811–3815. [PMID: 6933437] |
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| [EC 2.4.1.119 created 1984] |
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