| EC |
2.3.2.6 |
| Accepted name: |
leucyltransferase |
| Reaction: |
L-leucyl-tRNA + protein = tRNA + L-leucyl-protein |
| Other name(s): |
leucyl, phenylalanine-tRNA-protein transferase; leucyl-phenylalanine-transfer ribonucleate-protein aminoacyltransferase; leucyl-phenylalanine-transfer ribonucleate-protein transferase |
| Systematic name: |
L-leucyl-tRNA:protein leucyltransferase |
| Comments: |
Also transfers phenylalanyl groups. Requires a univalent cation. Peptides and proteins containing an N-terminal arginine, lysine or histidine residue can act as acceptors. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, METACYC, PDB, CAS registry number: 37257-22-0 |
| References: |
| 1. |
Leibowitz, M.J. and Soffer, R.L. A soluble enzyme from Escherichia coli which catalyzes the transfer of leucine and phenylalanine from tRNA to acceptor proteins. Biochem. Biophys. Res. Commun. 36 (1969) 47–53. [PMID: 4894363] |
| 2. |
Leibowitz, M.J. and Soffer, R.L. Enzymatic modification of proteins. 3. Purification and properties of a leucyl, phenylalanyl transfer ribonucleic acid protein transferase from Escherichia coli. J. Biol. Chem. 245 (1970) 2066–2073. [PMID: 4909560] |
| 3. |
Soffer, R.L. Peptide acceptors in the leucine, phenylalanine transfer reaction. J. Biol. Chem. 248 (1973) 8424–8428. [PMID: 4587124] |
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| [EC 2.3.2.6 created 1972, modified 1976] |
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