The Enzyme Database

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EC 2.3.2.6     
Accepted name: leucyltransferase
Reaction: L-leucyl-tRNALeu + protein = tRNALeu + L-leucyl-[protein]
Other name(s): leucyl, phenylalanine-tRNA-protein transferase; leucyl-phenylalanine-transfer ribonucleate-protein aminoacyltransferase; leucyl-phenylalanine-transfer ribonucleate-protein transferase; L-leucyl-tRNA:protein leucyltransferase
Systematic name: L-leucyl-tRNALeu:protein leucyltransferase
Comments: Also transfers phenylalanyl groups. Requires a univalent cation. Peptides and proteins containing an N-terminal arginine, lysine or histidine residue can act as acceptors.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 37257-22-0
References:
1.  Leibowitz, M.J. and Soffer, R.L. A soluble enzyme from Escherichia coli which catalyzes the transfer of leucine and phenylalanine from tRNA to acceptor proteins. Biochem. Biophys. Res. Commun. 36 (1969) 47–53. [PMID: 4894363]
2.  Leibowitz, M.J. and Soffer, R.L. Enzymatic modification of proteins. 3. Purification and properties of a leucyl, phenylalanyl transfer ribonucleic acid protein transferase from Escherichia coli. J. Biol. Chem. 245 (1970) 2066–2073. [PMID: 4909560]
3.  Soffer, R.L. Peptide acceptors in the leucine, phenylalanine transfer reaction. J. Biol. Chem. 248 (1973) 8424–8428. [PMID: 4587124]
[EC 2.3.2.6 created 1972, modified 1976, modified 2013]
 
 


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