| EC |
2.3.1.78 |
| Accepted name: |
heparan-α-glucosaminide N-acetyltransferase |
| Reaction: |
acetyl-CoA + heparan sulfate α-D-glucosaminide = CoA + heparan sulfate N-acetyl-α-D-glucosaminide |
| Other name(s): |
acetyl-CoA:α-glucosaminide N-acetyltransferase |
| Systematic name: |
acetyl-CoA:heparan-α-D-glucosaminide N-acetyltransferase |
| Comments: |
Brings about the acetylation of glucosamine groups of heparan sulfate and heparin from which the sulfate has been removed. Also acts on heparin. Not identical with EC 2.3.1.3 glucosamine N-acetyltransferase or EC 2.3.1.4 glucosamine-phosphate N-acetyltransferase. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 79955-83-2 |
| References: |
| 1. |
Klein, V., Kresse, H. and von Figura, K. Sanfilippo syndrome type C: deficiency of acetyl-CoA:α-glucosaminide N-acetyltransferase in skin fibroblasts. Proc. Natl. Acad. Sci. USA 75 (1978) 5185–5189. [DOI] [PMID: 33384] |
| 2. |
Pohlmann, R., Klein, U., Fromme, H.G. and von Figura, K. Localisation of acetyl-CoA: α-glucosaminide N-acetyltransferase in microsomes and lysosomes of rat liver. Hoppe-Seyler's Z. Physiol. Chem. 362 (1981) 1199–1207. [PMID: 7346380] |
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| [EC 2.3.1.78 created 1984] |
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