The Enzyme Database

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Accepted name: gentamicin 2′-N-acetyltransferase
Reaction: acetyl-CoA + gentamicin C1a = CoA + N2′-acetylgentamicin C1a
Glossary: kanamycin
Other name(s): gentamycin acetyltransferase II; gentamycin 2′-N-acetyltransferase; acetyl-CoA:gentamycin-C1a N2′-acetyltransferase
Systematic name: acetyl-CoA:gentamicin-C1a N2′-acetyltransferase
Comments: The antibiotics gentamicin A, sisomicin, tobramycin, paromomycin, neomycin B, kanamycin B and kanamycin C can also act as acceptors.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 50864-40-9
1.  Benveniste, R. and Davies, J. Aminoglycoside antibiotic-inactivating enzymes in actinomycetes similar to those present in clinical isolates of antibiotic-resistant bacteria. Proc. Natl. Acad. Sci. USA 70 (1973) 2276–2280. [PMID: 4209515]
[EC created 1976]

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