EC |
2.3.1.28 |
Accepted name: |
chloramphenicol O-acetyltransferase |
Reaction: |
acetyl-CoA + chloramphenicol = CoA + chloramphenicol 3-acetate |
Other name(s): |
chloramphenicol acetyltransferase; chloramphenicol acetylase; chloramphenicol transacetylase; CAT I; CAT II; CAT III |
Systematic name: |
acetyl-CoA:chloramphenicol 3-O-acetyltransferase |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9040-07-7 |
References: |
1. |
Shaw, W.V. The enzymatic acetylation of chloramphenicol by extracts of R factor-resistant Escherichia coli. J. Biol. Chem. 242 (1967) 687–693. [PMID: 5335032] |
2. |
Shaw, W.V. and Brodsky, R.F. Characterization of chloramphenicol acetyltransferase from chloramphenicol-resistant Staphylococcus aureus. J. Bacteriol. 95 (1968) 28–36. [PMID: 4965980] |
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[EC 2.3.1.28 created 1972] |
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