The Enzyme Database

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EC 2.3.1.28     
Accepted name: chloramphenicol O-acetyltransferase
Reaction: acetyl-CoA + chloramphenicol = CoA + chloramphenicol 3-acetate
Other name(s): chloramphenicol acetyltransferase; chloramphenicol acetylase; chloramphenicol transacetylase; CAT I; CAT II; CAT III
Systematic name: acetyl-CoA:chloramphenicol 3-O-acetyltransferase
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9040-07-7
References:
1.  Shaw, W.V. The enzymatic acetylation of chloramphenicol by extracts of R factor-resistant Escherichia coli. J. Biol. Chem. 242 (1967) 687–693. [PMID: 5335032]
2.  Shaw, W.V. and Brodsky, R.F. Characterization of chloramphenicol acetyltransferase from chloramphenicol-resistant Staphylococcus aureus. J. Bacteriol. 95 (1968) 28–36. [PMID: 4965980]
[EC 2.3.1.28 created 1972]
 
 


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