EC |
2.3.1.232 |
Accepted name: |
methanol O-anthraniloyltransferase |
Reaction: |
anthraniloyl-CoA + methanol = CoA + O-methyl anthranilate |
Glossary: |
anthraniloyl-CoA = 2-aminobenzoyl-CoA |
Other name(s): |
AMAT; anthraniloyl-coenzyme A (CoA):methanol acyltransferase |
Systematic name: |
anthraniloyl-CoA:methanol O-anthraniloyltransferase |
Comments: |
The enzyme from Concord grape (Vitis labrusca) is solely responsible for the production of O-methyl anthranilate, an important aroma and flavor compound in the grape. The enzyme has a broad substrate specificity, and can use a range of alcohols with substantial activity, the best being butanol, benzyl alcohol, iso-pentanol, octanol and 2-propanol. It can use benzoyl-CoA and acetyl-CoA as acyl donors with lower efficiency. In addition to O-methyl anthranilate, the enzyme might be responsible for the production of ethyl butanoate, methyl-3-hydroxy butanoate and ethyl-3-hydroxy butanoate, which are present in large quantities in the grapes. Also catalyses EC 2.3.1.196, benzyl alcohol O-benzoyltransferase. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Wang, J. and De Luca, V. The biosynthesis and regulation of biosynthesis of Concord grape fruit esters, including ’foxy’ methylanthranilate. Plant J. 44 (2005) 606–619. [DOI] [PMID: 16262710] |
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[EC 2.3.1.232 created 2014] |
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