The Enzyme Database

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EC 2.1.2.3     
Accepted name: phosphoribosylaminoimidazolecarboxamide formyltransferase
Reaction: 10-formyltetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide = tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide
For diagram of the late stages of purine biosynthesis, click here
Other name(s): 5-amino-4-imidazolecarboxamide ribonucleotide transformylase; AICAR transformylase; 10-formyltetrahydrofolate:5′-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase; 5′-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase; 5-amino-1-ribosyl-4-imidazolecarboxamide 5′-phosphate transformylase; 5-amino-4-imidazolecarboxamide ribotide transformylase; AICAR formyltransferase; aminoimidazolecarboxamide ribonucleotide transformylase
Systematic name: 10-formyltetrahydrofolate:5′-phosphoribosyl-5-amino-4-imidazole-carboxamide N-formyltransferase
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9032-03-5
References:
1.  Hartman, S.C. and Buchanan, J.M. Biosynthesis of the purines. XXVI. The identification of the formyl donors of the transformylation reaction. J. Biol. Chem. 234 (1959) 1812–1816. [PMID: 13672969]
[EC 2.1.2.3 created 1961, modified 2000]
 
 


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